Goat Anti-HVEM
Catalog Number :HZ53423 Quantity size : 0.1ml （dilute with pH 7.4 0.01 M PBS or antibody diluent ）
Background: Herpes virus entry mediator （HVEM）, a type I transmembrane protein, is a member of the TNF receptor superfamily. HVEM mediates the entry of herpes simplex virus （HSV） 1 and 2 into T lymphocytes by serving as an attach ment site for the HSV envelope glycoprotein D （gD）. HVEM also binds two cellular ligands, secreted lymphotoxin α and LIGHT. LIGHT is a member of the TNF superfamily produced by activated T cells. This type II transmembrane protein competes with HSV glycoprotein D for binding to HVEM. LIGHT is closely related in sequence to lymphotoxin β （LTβ） and can also bind to the LTβ receptor . LIGHT is also known to induce apoptosis and suppress tumor formation.
pecificity :
– Anti-HVEM is a Goat polyclonal antibody unconjugated.
– specific for HVEM of human, mouse, rat ,chicken
– use for western blotting,elisa,immunoprecipitation and immunohistochemistry
– Protein G affinity chromatography purification, purity :>95%
– Isotype: IgG
– mol wt: 30kDa
Application :
– Western blotting 1:100-500
– Immunohistochemistry 1:100-500
– ELISA 1:500-1000
– Optimal working dilutions must be determined by the end user.
Storage: Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody, the antibody is stable for at least six weeks at 2-4 ℃Goat Anti-HVEM
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Goat Anti-HVEM
